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Article

Tricarboranyl Pentaerythritol-Based Building Block

Supporting Info

Alexis Mollard and Ilya Zharov*

Department of Chemistry, University of Utah, Salt Lake City, Utah 84112

Inorg. Chem., 2006, 45 (25), pp 10172–10179

DOI: 10.1021/ic061297q

Publication Date (Web): November 9, 2006

To whom correspondence should be addressed. E-mail: zharov@ chem.utah.edu.

Abstract

A new tricarborane building block based on pentaerythritol was prepared for applications in boron neutron capture therapy (BNCT). Its X-ray single-crystal structure revealed a high degree of steric congestion. To enable the attachment of the building block to other moieties, a succinimidyl linker has been introduced at the focal point, and a generation-2 hexacarborane-containing dendron carrying 60 boron atoms has been prepared using a 2,2-bis(hydroxymethyl)propionic acid core.

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