Web Release Date: February 15,
Activity Increase of Horseradish Peroxidase in the Presence of Magnetic Particles

and
School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York 14853, and Department of Materials Science and Engineering, Cornell University, Ithaca, New York 14853
Received November 11, 2007

Abstract:
We report evidence for the effect of very low magnetic fields on a biological reaction. The presence of magnetite particles (with permanent magnetic moment of 1 emu/g) in the assay had a 30-fold increase on the rate of reaction of horseradish peroxidase. The activity of this enzyme was evaluated with two chromogen systems, and the apparent Michaelis-Menten kinetic parameters were extracted.
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