Web Release Date: January 10,
Hexagonally Packed Pd Nanoarray Catalyst for Liquid-Phase Enantioselective Hydrogenation of Acetophenone to R-(+)-1-Phenylethanol in the Presence of S-Proline
and
Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, P. R. China, and Wolfson Catalysis Centre, Inorganic Chemistry Laboratory, University of Oxford, South Parks Road, Oxford, OX1 3QR, U.K.
Received: November 17, 2007
In Final Form: January 2, 2008
Abstract:
Hexagonally packed Pd nanoarray catalyst was prepared via the "two solvents" strategy with mesoporous molecular sieve SBA-15 as a hard template. By using S-proline as the chiral modifier, the catalyst exhibited superior activity and selectivity in liquid-phase hydrogenation of acetophenone to R-(+)-1-phenylethanol with up to 100% chemoselectivity and 28.8% enantiomeric excess. The presence of S-proline and the regular hexagonal mesostructure of the Pd nanoarray catalyst are crucial for its superior catalytic performance.
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