Web Release Date: December 29,
New Method for Fabrication of Loaded Micro- and Nanocontainers: Emulsion Encapsulation by Polyelectrolyte Layer-by-Layer Deposition on the Liquid Core
and
Max-Planck Institute of Colloids and Interfaces, Golm/Potsdam, D-14476, Germany, and Shubnikov Institute of Crystallography, Russian Academy of Sciences, Leninskii pr. 59, Moscow, 119333, Russia
Received September 17, 2007
In Final Form: October 31, 2007
Abstract:
A novel approach to the emulsion encapsulation was developed by combining the advantages of direct encapsulation of a liquid colloidal core with the accuracy and multifunctionality of layer-by-layer polyelectrolyte deposition. Experimental data obtained for the model oil-in-water emulsion confirm unambiguously the alternating PE assembly in the capsule shell as well as the maintenance of the liquid colloidal core. Two different mechanisms of capsule destruction upon interaction with the solid substrate were observed and qualitatively explained. The proposed method can be easily generalized to the preparation of oil-filled capsules in various oil/water/polyelectrolyte systems important in the field of pharmacy, medicine, and food industry.
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