Org. Process Res. Dev., 11 (1), 64 -72, 2007. 10.1021/op0601060 S1083-6160(06)00106-X
Web Release Date: December 20, 2006

Copyright © 2006 American Chemical Society

Polymorphisms and Patent, Market, and Legal Battles: Cefdinir Case Study

Walter Cabri,* Paolo Ghetti, Giovanni Pozzi, and Marco Alpegiani

Antibioticos S.p.A., Research & Development, Strada Rivoltana km 6/7, 20089 Rodano, Milano, Italy

Received for review May 21, 2006.

Abstract:

The ongoing patent battle relating to Cefdinir polymorphism and crystalline forms is described from a scientific point of view. This case study illustrates some of the strategies adopted by generic bulk manufacturers to challenge originator's patents on polymorphic forms.


Download the full text: PDF | HTML