Synthesis of Highly Substituted
Cyclopentenones via the [4 + 1]
Cycloaddition of Nucleophilic Carbenes
and Vinyl Ketenes
James H. Rigby* andZhengqiang Wang
Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489
jhr@chem.wayne.edu
Received October 31, 2002
Abstract:
Vinyl ketenes have been shown to undergo [4 + 1] cycloaddition with a variety of nucleophilic carbenes to deliver highly substituted
cyclopentenones as products.
