Org. Lett., 9 (24), 4983 -4986, 2007. 10.1021/ol702176h S1523-7060(70)02176-4
Web Release Date: October 24, 2007

Copyright © 2007 American Chemical Society

1,2-Dihydroisoquinolines as Templates for Cascade Reactions To Access Isoquinoline Alkaloid Frameworks

Shun Su and John A. Porco, Jr.*

Department of Chemistry and Center for Chemical Methodology and Library Development (CMLD-BU), Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215

porco@bu.edu

Received September 4, 2007

Abstract:

The synthesis of isoquinoline alkaloid frameworks has been achieved via a series of cascade reactions identified through reaction discovery utilizing 1,2-dihydroisoquinoline scaffolds.

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