_tcm18-11415.gif )
An international journal for the quickest publication of high-quality research covering the breadth of synthetic, physical and biomolecular organic chemistry.
Subscribers
Free access
Emerging Area
Org. Biomol. Chem., 2003, 1, 3867 - 3870, DOI: 10.1039/b310752n
Diversity-oriented synthesis; a challenge for synthetic chemists
David R. Spring
The efficient, simultaneous synthesis of structurally diverse compounds, better known as diversity-oriented synthesis (DOS), is not obvious, and remains a challenge to synthetic chemistry. This personal account details why DOS has such enormous implications for the discovery of small molecules with desired properties, such as catalysts, synthetic reagents, biological probes and new drugs. Also, I describe the evolution behind the current state-of-play of DOS.
RSS feed
