Web Release Date: December 13,
Semiconductor Quantum Rods as Single Molecule Fluorescent Biological Labels
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Department of Chemistry, University of California Berkeley, California 94720, Department of Anatomy, University of California San Franscisco, California 94143, and Physical Biosciences Division and Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720
Received November 10, 2006
Abstract:
In this paper, we report the development of rod-shaped semiconductor nanocrystals (quantum rods) as fluorescent biological labels. Water-soluble biocompatible quantum rods have been prepared by surface silanization and applied for nonspecific cell tracking as well as specific cellular targeting. Quantum rods are brighter single molecule probes as compared to quantum dots. They have many potential applications as biological labels in situations where their properties offer advantages over quantum dots.
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