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Technical Note

Palm-Sized Biodetection System Based on Localized Surface Plasmon Resonance

Pavel Neuzil* and Julien Reboud

Institute of Microelectronics, 11 Science Park Road, Singapore Science Park II, Singapore 117685

Anal. Chem., 2008, 80 (15), pp 6100–6103

DOI: 10.1021/ac800335q

Publication Date (Web): July 1, 2008

* To whom correspondence should be addressed. E-mail: pavel@ime.a-star.edu.sg.

Abstract

We present a complete palm-sized, battery-operated biodetection system based on highly sensitive localized surface plasmon resonance (LSPR). We have replaced the spectrum analyzer by four pulse-powered light-emitting diodes (LED), each with different emission spectra. The reflected light beams from all LEDs were detected by a single photodiode. Its composite output current was demultiplexed by a four-channel lock-in amplifier. Device performance was demonstrated using an LSPR chip covered with a mixture of ethanol/water and 2-propanol/water at different concentrations. The miniaturized system does not require any external power supply or personal computer and it is therefore suitable for point-of-care and field applications.

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Published In Issue August 01, 2008
Article ASAPJuly 01, 2008
Received: February 18, 2008
Accepted: May 21, 2008

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Technical Note

Palm-Sized Biodetection System Based on Localized Surface Plasmon Resonance

Abstract

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Recommend & Share

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