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cDNA cloning of porcine brain prolyl endopeptidase and identification of the active-site seryl residue
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This article has been cited by 4 ACS Journal articles (4 most recent appear below).
The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease
Jonathan Z. Long and Benjamin F. CravattChemical Reviews2011 111 (10), 6022-6063The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease
Jonathan Z. Long and Benjamin F. CravattChemical Reviews2011 111 (10), 6022-6063
Synthesis and Characterization of the Novel Fluorescent Prolyl Oligopeptidase Inhibitor 4-Fluoresceinthiocarbamoyl- 6-aminocaproyl-l-prolyl-2(S)-(Hydroxy- acetyl)pyrrolidine
Jarkko I. Venäläinen, Erik A. A. Wallén, Antti Poso, J. Arturo García-Horsman, and Pekka T. MännistöJournal of Medicinal Chemistry2005 48 (23), 7093-7095Synthesis and Characterization of the Novel Fluorescent Prolyl Oligopeptidase Inhibitor 4-Fluoresceinthiocarbamoyl- 6-aminocaproyl-l-prolyl-2(S)-(Hydroxy- acetyl)pyrrolidine
Jarkko I. Venäläinen, Erik A. A. Wallén, Antti Poso, J. Arturo García-Horsman, and Pekka T. MännistöJournal of Medicinal Chemistry2005 48 (23), 7093-7095The synthesis and characterization of the first fluorescent prolyl oligopeptidase inhibitor 4-fluoresceinthiocarbamoyl-6-aminocaproyl-l-prolyl-2(S)-(hydroxyacetyl)pyrrolidine is described. This compound has an IC50 value of 0.83 nM and a dissociation half-...
A Prolyl Endopeptidase-Inhibiting Benzofuran Dimer from Polyozellus multiflex
Kyung-Sik Song and Ilya RaskinJournal of Natural Products2002 65 (1), 76-78A Prolyl Endopeptidase-Inhibiting Benzofuran Dimer from Polyozellus multiflex
Kyung-Sik Song and Ilya RaskinJournal of Natural Products2002 65 (1), 76-78A new benzofuran dimer, 5,6,5,6-tetrahydroxy[3,3]bibenzofuranyl-2,2-dicarboxylic acid dimethyl ester (kynapcin-24), was isolated from Polyozellus multiflex and shown to noncompetitively inhibit prolyl endopeptidase (PEP), with an IC50 value of 1.14 ...
New Prolyl Endopeptidase Inhibitors: In Vitro and in Vivo Activities of Azabicyclo[2.2.2]octane, Azabicyclo[2.2.1]heptane, and Perhydroindole Derivatives
Bernard Portevin, Alain Benoist, Georges Rémond, Yolande Hervé, Michel Vincent, Jean Lepagnol, and Guillaume De NanteuilJournal of Medicinal Chemistry1996 39 (12), 2379-2391New Prolyl Endopeptidase Inhibitors: In Vitro and in Vivo Activities of Azabicyclo[2.2.2]octane, Azabicyclo[2.2.1]heptane, and Perhydroindole Derivatives
Bernard Portevin, Alain Benoist, Georges Rémond, Yolande Hervé, Michel Vincent, Jean Lepagnol, and Guillaume De NanteuilJournal of Medicinal Chemistry1996 39 (12), 2379-2391A series of potent and selective prolylendopeptidase (PEP) inhibitors of the -keto heterocyclic type has been obtained by replacing the classical central proline of 1-[1-(4-phenylbutanoyl)-l-prolyl]pyrrolidine (SUAM 1221, 3) by non-natural amino acids ...
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- Published In Issue February, 1991
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