Three-dimensional structure of interleukin 8 in solution

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This article has been cited by 46 ACS Journal articles (5 most recent appear below).

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  Chemical Synthesis of Intentionally Misfolded Homogeneous Glycoprotein: A Unique Approach for the Study of Glycoprotein Quality Control

  Masayuki Izumi, Yutaka Makimura, Simone Dedola, Akira Seko, Akiko Kanamori, Masafumi Sakono, Yukishige Ito, and Yasuhiro Kajihara
  Journal of the American Chemical Society2012 134 (17), 7238-7241

  • Chemical Synthesis of Intentionally Misfolded Homogeneous Glycoprotein: A Unique Approach for the Study of Glycoprotein Quality Control

    Masayuki Izumi, Yutaka Makimura, Simone Dedola, Akira Seko, Akiko Kanamori, Masafumi Sakono, Yukishige Ito, and Yasuhiro Kajihara
    Journal of the American Chemical Society2012 134 (17), 7238-7241

    Biosynthesis of glycoproteins in the endoplasmic reticulum employs a quality control system, which discriminates and excludes misfolded malfunctional glycoproteins from a correctly folded one. As chemical tools to study the glycoprotein quality control ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
• 

  Molecular Dynamics Simulations of CXCL-8 and Its Interactions with a Receptor Peptide, Heparin Fragments, and Sulfated Linked Cyclitols

  Neha S. Gandhi and Ricardo L. Mancera
  Journal of Chemical Information and Modeling2011 51 (2), 335-358

  • Molecular Dynamics Simulations of CXCL-8 and Its Interactions with a Receptor Peptide, Heparin Fragments, and Sulfated Linked Cyclitols

    Neha S. Gandhi and Ricardo L. Mancera
    Journal of Chemical Information and Modeling2011 51 (2), 335-358

    CXCL-8 (Interleukin 8) is a CXC chemokine with a central role in the human immune response. We have undertaken extensive in silico analyses to elucidate the interactions of CXCL-8 with its various binding partners, which are crucial for its biological ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
• 

  X-ray Crystallographic Structure of an Artificial β-Sheet Dimer

  Omid Khakshoor, Aaron J. Lin, Tyler P. Korman, Michael R. Sawaya, Shiou-Chuan Tsai, David Eisenberg, and James S. Nowick
  Journal of the American Chemical Society2010 132 (33), 11622-11628

  • X-ray Crystallographic Structure of an Artificial β-Sheet Dimer

    Omid Khakshoor, Aaron J. Lin, Tyler P. Korman, Michael R. Sawaya, Shiou-Chuan Tsai, David Eisenberg, and James S. Nowick
    Journal of the American Chemical Society2010 132 (33), 11622-11628

    This paper describes the X-ray crystallographic structure of a designed cyclic β-sheet peptide that forms a well-defined hydrogen-bonded dimer that mimics β-sheet dimers formed by proteins. The 54-membered ring macrocyclic peptide (1a) contains molecular ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
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  Structure of Chemokine-Derived Antimicrobial Peptide Interleukin-8α and Interaction with Detergent Micelles and Oriented Lipid Bilayers

  Sarah Bourbigot, Liam Fardy, Alan J. Waring, Michael R. Yeaman and Valerie Booth
  Biochemistry2009 48 (44), 10509-10521

  • Structure of Chemokine-Derived Antimicrobial Peptide Interleukin-8α and Interaction with Detergent Micelles and Oriented Lipid Bilayers

    Sarah Bourbigot, Liam Fardy, Alan J. Waring, Michael R. Yeaman and Valerie Booth
    Biochemistry2009 48 (44), 10509-10521

    Interleukin-8α (IL-8α) is an antimicrobial peptide derived from the chemokine IL-8. Solution NMR was used to determine the atomic-resolution structure of IL-8α in SDS micelles. Solid-state NMR and tryptophan fluorescence were used to probe the interaction ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
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  Structural Basis for Differential Binding of the Interleukin-8 Monomer and Dimer to the CXCR1 N-Domain: Role of Coupled Interactions and Dynamics

  Aishwarya Ravindran, Prem Raj B. Joseph and Krishna Rajarathnam
  Biochemistry2009 48 (37), 8795-8805

  • Structural Basis for Differential Binding of the Interleukin-8 Monomer and Dimer to the CXCR1 N-Domain: Role of Coupled Interactions and Dynamics

    Aishwarya Ravindran, Prem Raj B. Joseph and Krishna Rajarathnam
    Biochemistry2009 48 (37), 8795-8805

    Interleukin-8 (IL-8 or CXCL8) plays a critical role in orchestrating the immune response by binding and activating the receptor CXCR1 that belongs to the GPCR class. IL-8 exists as both monomers and dimers, and both bind CXCR1 but with differential ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links

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