Process-Driven Information Management System at a Biotech Company:  Concept and Implementation

Alberto Gobbi,* Sandra Funeriu, John Ioannou, Jinyi Wang, and Man-Ling Lee*
Anadys Pharmaceuticals, Inc., San Diego, California 92121
Chris Palmer and Bob Bamford
Managed Ventures, LLC., Irvine, California 92618
Robin Hewitt
Hewitt Consulting, San Diego, California 92150
J. Chem. Inf. Comput. Sci., 2004, 44 (3), pp 964–975
DOI: 10.1021/ci034269o
Publication Date (Web): March 12, 2004
Copyright © 2004 American Chemical Society
*

 Corresponding authors phone:  +1 (858) 530 3657; e-mail:  agobbi@ anadyspharma.com (A.G.) and phone:  +1 (858) 530 3658; e-mail:  mlee@anadyspharma.com (M.-L.L.).

Abstract

While established pharmaceutical companies have chemical information systems in place to manage their compounds and the associated data, new startup companies need to implement these systems from scratch. Decisions made early in the design phase usually have long lasting effects on the expandability, maintenance effort, and costs associated with the information management system. Careful analysis of work and data flows, both inter- and intradepartmental, and identification of existing dependencies between activities are important. This knowledge is required to implement an information management system, which enables the research community to work efficiently by avoiding redundant registration and processing of data and by timely provision of the data whenever needed. This paper first presents the workflows existing at Anadys, then ARISE, the research information management system developed in-house at Anadys. ARISE was designed to support the preclinical drug discovery process and covers compound registration, analytical quality control, inventory management, high-throughput screening, lower throughput screening, and data reporting.

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History

  • Published In Issue May 24, 2004
  • Received November 17, 2003

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