Prev. Article Next Article Table of Contents

Research Article

Concept Design of Computer-Aided Study on Traditional Chinese Drugs

Figures
Citing Articles

Your current credentials do not allow retrieval of the full text.

Purchase the full-text

PDF/HTML,
figures/images,
references and tables,
(where available)

Xinjian Yan,* Jiaju Zhou, and Zhihong Xu

Laboratory of Computer Chemistry, Institute of Chemical Metallurgy, Chinese Academy of Sciences, P.O. Box 353, Beijing 100080, China

J. Chem. Inf. Comput. Sci., 1999, 39 (1), pp 86–89

DOI: 10.1021/ci980143t

Publication Date (Web): December 18, 1998

Section:

Pharmacology

Abstract

Traditional Chinese drugs (TCDs) have played a key role for Chinese people in the treatment of diseases since ancient times. The use of TCDs has generated a great amount of information in the past thousand years about the relationship between natural products and the human body. However, up to now, our understanding on the mode of action of the TCD is still limited. Considering that the basic mechanism of all drug function involves the interaction between the drug and biological receptors at the molecular level, we propose to connect TCDs with modern medicine theory through molecular structures. We propose to explain functions of TCDs by using the knowledge developed in modern molecular biology, pharmacology, computer chemistry, and biochemistry. We are working on a computer-aided Chinese drug study that is discussed in this paper. A short introduction on the progress of our research is also given.

View: Full Text HTML | Hi-Res PDF | PDF w/ Links

Citing Articles

View all 4 citing articles

Citation data is made available by participants in CrossRef's Cited-by Linking service. For a more comprehensive list of citations to this article, users are encouraged to perform a search in SciFinder.

This article has been cited by 3 ACS Journal articles (3 most recent appear below).

CHMIS-C: A Comprehensive Herbal Medicine Information System for Cancer
Xueliang Fang, Lei Shao, Hui Zhang, and Shaomeng Wang
Journal of Medicinal Chemistry2005 48 (5), 1481-1488
- CHMIS-C: A Comprehensive Herbal Medicine Information System for Cancer
  Xueliang Fang, Lei Shao, Hui Zhang, and Shaomeng Wang
  Journal of Medicinal Chemistry2005 48 (5), 1481-1488
  A comprehensive herbal medicine information system for cancer (CHMIS-C) has been developed. The current version of the database integrates information on more than 200 anticancer herbal recipes that have been used for the treatment of different types of ...
  Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
A Marine Natural Product Database
Jing Lei and Jiaju Zhou
Journal of Chemical Information and Computer Sciences2002 42 (3), 742-748
- A Marine Natural Product Database
  Jing Lei and Jiaju Zhou
  Journal of Chemical Information and Computer Sciences2002 42 (3), 742-748
  A database of marine natural products has been developed. The database contains approximately 6000 chemical compounds derived from over 10 000 marine-derived materials. For each compound, the structure, physical and chemical properties, marine source, and ...
  Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
Traditional Chinese Medicine Database and Application on the Web
Min He, Xinjian Yan, Jiaju Zhou, and Guirong Xie
Journal of Chemical Information and Computer Sciences2001 41 (2), 273-277
- Traditional Chinese Medicine Database and Application on the Web
  Min He, Xinjian Yan, Jiaju Zhou, and Guirong Xie
  Journal of Chemical Information and Computer Sciences2001 41 (2), 273-277
  To study traditional Chinese medicines and exchange related information through the worldwide Web, we developed a traditional Chinese medicine database and a program for searching and displaying data in the database on the Web. In this paper, the ...
  Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links