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Thin-Layer Chromatography of Analgesics-An Update

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John W. Elder

Fairfield University, Fairfield, CT 06430

J. Chem. Educ., 1995, 72 (11), p 1049

DOI: 10.1021/ed072p1049

Publication Date: November 1995

Abstract

Acetominaphen, aspirin, caffeine, ibuprofen, and naproxensodium are determined by thin-layer chromatography.

Keywords (Audience):

Second-Year Undergraduate

Keywords (Domain):

Organic Chemistry

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Chromatography

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Citing Articles

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This article has been cited by 3 ACS Journal articles (3 most recent appear below).

Separation of the Components of a Commercial Analgesic Tablet: A Two-Week Sequence Comparing Purification by Two-Base Extraction and Column Chromatography
Kevin D. Revell
Journal of Chemical Education2011 Article ASAP
- Separation of the Components of a Commercial Analgesic Tablet: A Two-Week Sequence Comparing Purification by Two-Base Extraction and Column Chromatography
  Kevin D. Revell
  Journal of Chemical Education2011 Article ASAP
  A new laboratory experiment is described in which students compare two benchtop separation methods to isolate the three active components of the commercial analgesic Excedrin. In the two-week sequence, aspirin, acetaminophen, and caffeine are separated ...
  Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
Synthesis of Ibuprofen in the Introductory Organic Laboratory
Richard A. Kjonaas, Peggy E. Williams, David A. Counce, and Lindsey R. Crawley
Journal of Chemical Education2011 88 (6), 825-828
- Synthesis of Ibuprofen in the Introductory Organic Laboratory
  Richard A. Kjonaas, Peggy E. Williams, David A. Counce, and Lindsey R. Crawley
  Journal of Chemical Education2011 88 (6), 825-828
  A method for the synthesis of ibuprofen in introductory organic chemistry laboratory courses is reported. This experiment requires two 3-h lab sessions. All of the reactions and techniques are a standard part of any introductory organic chemistry course. ...
  Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
Planar Chromatography
Joseph Sherma
Analytical Chemistry1998 70 (12), 7-26
- Planar Chromatography
  Joseph Sherma
  Analytical Chemistry1998 70 (12), 7-26
  Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links