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Disconnect by the Numbers: Protocol for the Synthesis of Alkanes

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Michael B. Smith

University of Connecticut, Storrs, CT 06269

J. Chem. Educ., 1996, 73 (4), p 304

DOI: 10.1021/ed073p304

Publication Date (Web): April 1, 1996

Section:

History, Education, and Documentation

Abstract

The synthesis of alkanes is an important tool for teaching organic chemistry. The original disconnect by the numbers protocol for the design of synthetic routes could not be used with alkanes due to the lack of a functional group. This addendum gives a method to convert an alkane to a functionalized precursor and that new molecule can be analyzed in the normal manner.