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When Drug Molecules Look in the Mirror
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Abstract
Enantiomers possess virtually identical physical properties but often display very different biological activities. Stereochemical non-equivalence, chiral recognition, enantiomer uniqueness, and the preparation of optically active drugs are reviewed. Pertinent information for selected racemic and single enantiomer drugs are provided.
Keywords (Audience):
Second-Year UndergraduateKeywords (Domain):
Organic ChemistryKeywords (Subject):
EnantiomersCiting Articles
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This article has been cited by 2 ACS Journal articles (2 most recent appear below).

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Steven C. Cermak and David F. WiemerJournal of Chemical Education1999 76 (12), 1715The preparation of optically active (camphorsulfonyl)oxaziridines from commercially available (1R)-(-) and/or (1S)-(+)10-camphorsulfonic acid provides a clear demonstration of the lack of relationship between absolute configuration and optical rotation. ...

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History
- Received: August 03, 2009
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