Lab-Expt
Synthesis and Use of Reverse-Phase Silica Gel for HPLC in Undergraduate Chemistry
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Abstract
Commercially available silica gel was derivatized with n-octadecyldimethylchlorosilane to produce inexpensive HPLC reverse-phase stationary support, which was used in separation experiments.
Keywords (Audience):
Second-Year UndergraduateKeywords (Domain):
Organic ChemistryKeywords (Feature):
The Modern Student LaboratoryKeywords (Pedagogy):
Hands-On Learning / ManipulativesKeywords (Subject):
HPLCCiting Articles
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This article has been cited by 1 ACS Journal articles (1 most recent appear below).

Preparation and Characterization of a Polymeric Monolithic Column for Use in High-Performance Liquid Chromatography (HPLC)
Michael P. Bindis, Stacey Lowery Bretz, and Neil D. DanielsonJournal of Chemical Education2011 88 (5), 675-678Preparation and Characterization of a Polymeric Monolithic Column for Use in High-Performance Liquid Chromatography (HPLC)
Michael P. Bindis, Stacey Lowery Bretz, and Neil D. DanielsonJournal of Chemical Education2011 88 (5), 675-678The high-performance liquid chromatography (HPLC) experiment, most often done in the undergraduate analytical instrumentation laboratory course, generally illustrates reversed-phase chromatography using a commercial C18 silica column. To avoid the expense ...
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History
- Received: August 03, 2009
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