Synthesis and Use of Reverse-Phase Silica Gel for HPLC in Undergraduate Chemistry

Fernando Ortega , Ernesto Velez and Ratnassamy Somanathan
Centro De Graduados, Instituto Technologico De Tijuana, Apdo. postal 11 66, 22000 Tijuana, B.C. Mexico
J. Chem. Educ., 1996, 73 (2), p A26
DOI: 10.1021/ed073pA26
Publication Date (Web): February 1, 1996

Abstract

Commercially available silica gel was derivatized with n-octadecyldimethylchlorosilane to produce inexpensive HPLC reverse-phase stationary support, which was used in separation experiments.

Keywords (Audience):

Second-Year Undergraduate

Keywords (Domain):

Organic Chemistry

Keywords (Feature):

The Modern Student Laboratory

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

HPLC

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History

  • Received: August 03, 2009

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