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Evolution of Blood Chemistry Analyzers Based on Ion Selective Electrodes
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Abstract
Ion selective electrodes and some electrochemical sensors, owing to their unique ability to directly sense analytes, are well suited for whole blood, plasma, and serum critical analyte testing. These critical analytes are major electrolytes, blood gases, and some metabolites. Analyzers based on ion selective electrodes (ISE) can provide fast turnaround time (TAT) for critical care testing.
Following their historical development, these instruments can be conveniently divided into the following products: arterial blood gas (ABG) analyzers; electrolyte analyzers; integrated blood gas/electrolyte analyzers; and integrated blood gas/electrolyte/metabolite analyzers. This presentation will trace the development of these analyzers. The single-use disposable cartridge will not be included.
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Ion Selective ElectrodesCiting Articles
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This article has been cited by 7 ACS Journal articles (5 most recent appear below).

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Investigation of Cu(II) Binding to Bovine Serum Albumin by Potentiometry with an Ion Selective Electrode: A Biophysical Chemistry Experiment for the Undergraduate Curriculum
Jie LiuJournal of Chemical Education2004 81 (3), 395Investigation of Cu(II) Binding to Bovine Serum Albumin by Potentiometry with an Ion Selective Electrode: A Biophysical Chemistry Experiment for the Undergraduate Curriculum
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Tuning and Dissecting Electronic and Steric Effects in Ammonium Receptors: Nonactin vs Artificial Receptors
Jik Chin, Jinho Oh, Sang Yong Jon, Sang Hyun Park, Christian Walsdorff, Brent Stranix, Assaad Ghoussoub, Seok Jong Lee, Hyun Jei Chung, Su-Moon Park, and Kimoon KimJournal of the American Chemical Society2002 124 (19), 5374-5379Tuning and Dissecting Electronic and Steric Effects in Ammonium Receptors: Nonactin vs Artificial Receptors
Jik Chin, Jinho Oh, Sang Yong Jon, Sang Hyun Park, Christian Walsdorff, Brent Stranix, Assaad Ghoussoub, Seok Jong Lee, Hyun Jei Chung, Su-Moon Park, and Kimoon KimJournal of the American Chemical Society2002 124 (19), 5374-5379Ion selective electrodes (ISE) based on three different tripodal receptors (5, 6, and 7) have been investigated for sensing ammonium ion. Each receptor is based on three pyrazole groups that can accept three H-bonds from the bound ammonium ion. The ...
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- Received: August 03, 2009
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