Understanding the Quadrupole Mass Filter through Computer Simulation

Michael Henchman and Colin Steel
Department of Chemistry, Brandeis University, Waltham, MA 02254
J. Chem. Educ., 1998, 75 (8), p 1049
DOI: 10.1021/ed075p1049
Publication Date (Web): August 1, 1998

Abstract

The main features of the stability diagram for a quadrupole mass filter can be understood qualitatively using two concepts: (i) moderate RF voltages stabilize a trajectory; (ii) large RF voltages destabilize a trajectory. The trajectories of the ions traveling in the quadrupole are readily displayed pictorially for any set of operating conditions. These are computed as a straightforward student exercise, integrating numerically the equations of motion of the ion in the quadrupole electric field. The outcome of these trajectories-whether the ion is transmitted or deflected-allows us to map the stability diagram. The stability diagram reveals how the quadrupole acts as a mass filter and delivers a mass spectrum. The characteristic features of the trajectories are complicated and varied; and they are obtained for each region of the stability diagram. Explanations for some of these features are developed by examining the forces on the ion as it proceeds through the quadrupole.

Keywords (Audience):

Upper-Division Undergraduate

Keywords (Domain):

Laboratory Instruction

Keywords (Pedagogy):

Computer-Based Learning

Keywords (Subject):

Instrumental Methods
View: Hi-Res PDF | PDF w/ Links

Tools

SciFinder Links

SciFinder subscribers: Click to sign in | Not a SciFinder subscriber? Learn more at www.cas.org

Explore by:

History

  • Received: August 03, 2009

Recommend & Share

  • Share on ACS NetworkACS Network
  • Add to FacebookFacebook
  • Tweet ThisTweet This
  • Add to CiteULikeCiteULike
  • Add to NewsvineNewsvine
  • Digg ThisDigg This
  • Add to DeliciousDelicious

Related Content