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Production, Extraction, and Qualitative Testing of Penicillin: A Biochemistry Experiment for Health Science Chemistry Courses

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Richard E. Stevens and Kara C. Billingsley

Department of Chemistry, Whitworth College, Spokane, WA 99251

J. Chem. Educ., 1998, 75 (10), p 1264

DOI: 10.1021/ed075p1264

Publication Date (Web): October 1, 1998

Section:

History, Education, and Documentation

Abstract

This laboratory procedure guides students through the growth of a submerged Penicillium chrysogenum culture. Subsequent steps include extraction of the penicillin by adsorption onto activated charcoal, extraction with acetone, and qualitative testing of the drug on a bacterial culture. The laboratory procedure is designed for freshman-level health science chemistry courses. This procedure produces minimal waste, which can be disposed of by the appropriate use of an autoclave.

Keywords (Audience):

First-Year Undergraduate / General

Keywords (Domain):

Biochemistry

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Drugs / Pharmaceuticals

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Received: August 03, 2009

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Article

Production, Extraction, and Qualitative Testing of Penicillin: A Biochemistry Experiment for Health Science Chemistry Courses

Abstract

Keywords (Audience):

Keywords (Domain):

Keywords (Pedagogy):

Keywords (Subject):

Tools

SciFinder Links

History

Recommend & Share

Related Content

A Non-Mercury Thermometer Alternative for Use in Older Melting Point Apparatuses

Explosive Limits of Industrial Gases

Determination of Hammett Equation Rho Constant for the Hydrolysis of p-Nitrophenyl Benzoate Esters

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