Determination of Chloride Concentration Using Capillary Zone Electrophoresis: An Instrumental Analysis Chemistry Laboratory Experiment

Michael A. Janusa , Lawrence J. Andermann , Nicole M. Kliebert and Mark H. Nannie
Department of Physical Sciences, Nicholls State University, Thibodaux, LA 70310
J. Chem. Educ., 1998, 75 (11), p 1463
DOI: 10.1021/ed075p1463
Publication Date (Web): November 1, 1998

Abstract

The determination of the concentration of inorganic anions can be accomplished by using capillary zone electrophoresis (CZE). Since this is a fairly new analytical technique showing tremendous promise, it should be introduced to students at the undergraduate level. Herein, we describe a CZE experiment developed for instrumental analysis chemistry laboratory that can be modified for other species or substances.

Keywords (Audience):

Upper-Division Undergraduate

Keywords (Domain):

Laboratory Instruction

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Instrumental Methods

Citing Articles

View all 6 citing articles

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This article has been cited by 6 ACS Journal articles (5 most recent appear below).

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    Capillary Electrophoresis: Focus on Undergraduate Laboratory Experiments

    Lisa A. Holland
    Journal of Chemical Education2011 88 (3), 254-256
    • Capillary Electrophoresis: Focus on Undergraduate Laboratory Experiments

      Lisa A. Holland
      Journal of Chemical Education2011 88 (3), 254-256

      Capillary electrophoresis is a versatile technique well suited to teach concepts that are fundamental to a chemistry degree program. The applicability of capillary electrophoresis to metabolites, DNA, proteins, pharmaceutical compounds, environmental ...

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    Weak Acid pKa Determination Using Capillary Zone Electrophoresis

    Mike Solow
    Journal of Chemical Education2006 83 (8), 1194
    • Weak Acid pKa Determination Using Capillary Zone Electrophoresis

      Mike Solow
      Journal of Chemical Education2006 83 (8), 1194

      This article describes a general chemistry experiment designed to measure the pKa of benzoic acid using capillary zone electrophoresis. Despite the fact that modern biology relies so heavily on this analytical technique, students get very little ...

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    Capillary Electrophoresis Analysis of Cations in Water Samples. An Experiment for the Introductory Laboratory

    Christopher J. Pursell , Bert Chandler and Michelle M. Bushey
    Journal of Chemical Education2004 81 (12), 1783
    • Capillary Electrophoresis Analysis of Cations in Water Samples. An Experiment for the Introductory Laboratory

      Christopher J. Pursell , Bert Chandler and Michelle M. Bushey
      Journal of Chemical Education2004 81 (12), 1783

      Capillary electrophoresis is gradually working its way into the undergraduate laboratory curriculum. Typically, experiments utilizing this newer technology have been introduced into analytical or instrumental courses. We have introduced an experiment into ...

  • Cover Image

    Determination of a Diffusion Coefficient by Capillary Electrophoresis. An Experiment for the Physical and Biophysical Chemistry Laboratories

    Kathryn R. Williams , Bhavin Adhyaru , Igor German and Thomas Russell
    Journal of Chemical Education2002 79 (12), 1475
    • Determination of a Diffusion Coefficient by Capillary Electrophoresis. An Experiment for the Physical and Biophysical Chemistry Laboratories

      Kathryn R. Williams , Bhavin Adhyaru , Igor German and Thomas Russell
      Journal of Chemical Education2002 79 (12), 1475

      Students measure the diffusion coefficient of dopamine (3-hydroxytyramine) by capillary electrophoresis using three evaluation methods: single-point, graphical, and stopped migration. The experiment combines instruction of modern instrumentation with the ...

  • Cover Image

    The Escalator—An Analogy for Explaining Electroosmotic Flow

    Andrew J. Vetter and Garrett J. McGowan
    Journal of Chemical Education2001 78 (2), 209
    • The Escalator—An Analogy for Explaining Electroosmotic Flow

      Andrew J. Vetter and Garrett J. McGowan
      Journal of Chemical Education2001 78 (2), 209

      Capillary electrophoresis (CE) is an instrumental technique that is rapidly gaining popularity for use in the undergraduate laboratory. As a result, it becomes necessary to integrate the topic of CE into the junior/senior-level instrumental analysis ...

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  • Received: August 03, 2009

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