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Conformation Interchange in Nuclear Magnetic Resonance Spectroscopy
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Abstract
Intramolecular dynamics are readily discernible by use of nuclear magnetic resonance spectrometry. A relatively simple laboratory tutorial experiment demonstrating such motion, an internal interchange of conformations, in a readily available nitroaromatic hydrazine (2,2-diphenyl-1-picrylhydrazine in liquid solution) is presented and discussed. Simple computer analysis of the 1H line shapes taken on standard NMR equipment at several temperatures produces the activation energy (as well as the pseudothermodynamic enthalpy, entropy, and Gibbs free-energy changes) for the process. The molecular basis for the molecular motion is easily visualizable.
Keywords (Audience):
Second-Year UndergraduateKeywords (Domain):
Laboratory InstructionKeywords (Pedagogy):
Hands-On Learning / ManipulativesKeywords (Subject):
Magnetic PropertiesCiting Articles
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This article has been cited by 4 ACS Journal articles (4 most recent appear below).
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Zbigniew L. Gasyna and Antoni JurkiewiczJournal of Chemical Education2004 81 (7), 1038A 13C NMR experiment is proposed in which spin–lattice relaxation time T1 is determined for carbon atoms in a sample of liquid n-hexanol. The effective correlation times for rotational reorientation are calculated to determine the relative mobility of ...
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- Received: August 03, 2009
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