Prev. Article Next Article Table of Contents

Lab-Expt

Convenient Synthesis of a Lactone, γ-Butyrolactone

Your current credentials do not allow retrieval of the full text.

Purchase the full-text

PDF/HTML,
figures/images,
references and tables,
(where available)

Richard E. Bozak , J. Knittel and Ronald J. Hicks

California State University, Hayward, Department of Chemistry, Hayward, CA 94542-3089

J. Chem. Educ., 1998, 75 (1), p 84

DOI: 10.1021/ed075p84

Publication Date (Web): January 1, 1998

Section:

History, Education, and Documentation

Abstract

A five-membered cyclic ester, gamma-Butyrolactone, was prepared from GHB using a microscale reflux method. Cyclization yielded a product with a boiling point significantly greater (by 129 °C) than that of the open-chain analogue.

Keywords (Audience):

Second-Year Undergraduate

Keywords (Domain):

Laboratory Instruction

Keywords (Feature):

The Microscale Laboratory

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Microscale Lab

View: Hi-Res PDF | PDF w/ Links

Tools

SciFinder Links

Explore by:

Author of this Article Any Author Research Topic

History

Received: August 03, 2009

Recommend & Share

Related Content

Investigation of Atropisomerism in ortho-Substituted Tetraphenylporphyrins: An Experimental Module Involving Synthesis, Chromatography, and NMR SpectroscopyJournal of Chemical Education
- Investigation of Atropisomerism in ortho-Substituted Tetraphenylporphyrins: An Experimental Module Involving Synthesis, Chromatography, and NMR Spectroscopy
  Ruth Freitag Beeston , Shannon E. Stitzel and Mitchell A. Rhea
  Journal of Chemical Education 1997 74 (12), p 1468
  Abstract:
  An experimental module suitable for advanced undergraduates is described. This module begins with the synthesis of tetra(o-tolyl)porphyrin (T(o-Tol)P), which exists as a statistical distribution of atropisomers due to hindered rotation about the porphine-...
  Abstract | PDF w/ Links | Hi-Res PDF
An Efficient Microscale Procedure for the Synthesis of AspirinJournal of Chemical Education
- An Efficient Microscale Procedure for the Synthesis of Aspirin
  Sangeeta Pandita and Samta Goyal
  Journal of Chemical Education 1998 75 (6), p 770
  Abstract:
  The synthesis of aspirin is a part of many undergraduate organic synthesis labs and is frequently used in qualitative organic analysis laboratory for the identification of salicylic acid. We have found that aspirin can be synthesized on microscale by a ...
  Abstract | PDF w/ Links | Hi-Res PDF
A Microscale Synthesis of the Diastereomers of 2,3-Dibromosuccinic AcidJournal of Chemical Education
- A Microscale Synthesis of the Diastereomers of 2,3-Dibromosuccinic Acid
  John Tomsho , James R. McKee and Murray Zanger
  Journal of Chemical Education 1999 76 (1), p 73
  Abstract: Microscale procedures for the synthesis of meso- and racemic-2,3-dibromosuccinic acids are described. The methods differ from standard large-scale syntheses of these compounds and the rationale for the changes is explained.
  Abstract | PDF w/ Links | Hi-Res PDF

Select a CAS section from the 5 main topical divisions below:

Lab-Expt

Convenient Synthesis of a Lactone, γ-Butyrolactone

Abstract

Keywords (Audience):

Keywords (Domain):

Keywords (Feature):

Keywords (Pedagogy):

Keywords (Subject):

Tools

SciFinder Links

History

Recommend & Share

Related Content

Investigation of Atropisomerism in ortho-Substituted Tetraphenylporphyrins: An Experimental Module Involving Synthesis, Chromatography, and NMR Spectroscopy

An Efficient Microscale Procedure for the Synthesis of Aspirin

A Microscale Synthesis of the Diastereomers of 2,3-Dibromosuccinic Acid

See also:

JOURNALS

BOOKS

C&EN

TOOLS

COMMUNITIES

DIRECTORIES & DATABASES

LEGACY MAGAZINES

Products

User Resources

Support

Partners

Search ACS Publications