Introducing Chiroscience into the Organic Laboratory Curriculum

Kenny B. Lipkowitz , Tim Naylor and Keith S. Anliker
Department of Chemistry, Indiana University Purdue University at Indianapolis, 402 N. Blackford Street, Indianapolis, IN 46202-3274
J. Chem. Educ., 2000, 77 (3), p 305
DOI: 10.1021/ed077p305
Publication Date (Web): March 1, 2000

Abstract

Chirality transcends traditional boundaries separating subdisciplines of the chemical sciences. The large number of scientific studies focusing on the topic of chirality has now thrust it into the scientific forefront, especially in biological and organic chemistry but more recently in inorganic and organometallic chemistry. Reflecting this interest are new journals dedicated to this topic, including: Tetrahedron: Asymmetry, Enantiomer, Chirality, and Molecular Asymmetry, all of which complement existing journals that are themselves replete with papers on chirality. When our proposal to the National Science Foundation was written, we looked at the 1996 Journal of Organic Chemistry and found that 23% of all papers focused explicitly on chirality, with an additional 27% involving stereochemistry. For Tetrahedron Letters, the numbers were 18% and 29% respectively. Workshops, symposia and conferences dedicated to chirality are now common and popular. Further attesting to the significance of this topic was a series of feature articles in CandE News laying bare the fact that a whole new industry based on chirality now exists (1). This industry, designated as "chiroscience", is a young but robust industry linking science and technology with chemistry and biology.

Keywords (Audience):

Second-Year Undergraduate

Keywords (Domain):

Organic Chemistry

Keywords (Feature):

NSF Highlights

Keywords (Subject):

Chirality / Optical Activity

Citing Articles

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This article has been cited by 6 ACS Journal articles (5 most recent appear below).

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    • Synthesis and Resolution of the Atropisomeric 1,1'-Bi-2-naphthol: An Experiment in Organic Synthesis and 2-D NMR Spectroscopy

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    • Chiral Compounds and Green Chemistry in Undergraduate Organic Laboratories: Reduction of a Ketone by Sodium Borohydride and Baker's Yeast

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  • Received: August 03, 2009

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