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Experiments with Aspirin

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Edward Barry

El Camino High School, Sacramento, CA 95821

Londa L. Borer

Department of Chemistry, California State University, Sacramento,Sacramento, CA 95819

J. Chem. Educ., 2000, 77 (3), p 354

DOI: 10.1021/ed077p354

Publication Date (Web): March 1, 2000

Abstract

A series of experiments based on aspirin have been used in our high school chemistry laboratory. Experiments include (i) synthesis, purification, and characterization of aspirin by mp and TLC, (ii) percentage composition of a commercial aspirin tablet by titration, (iii) kinetics of the hydrolysis of aspirin to salicylic acid under various conditions, (iv) synthesis and characterization of copper(II) aspirinate and copper(II) salicylate, and (v) reaction of copper(II) aspirinate in aqueous solution.

Keywords (Audience):

High School / Introductory Chemistry

Keywords (Domain):

Organic Chemistry

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Synthesis

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Received: August 03, 2009

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Experiments with Aspirin

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Synthesis of Aspirin: A General Chemistry Experiment

The aspirin project. Laboratory experiments for introductory chemistry

Method development for analysis of aspirin tablets

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