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Microwave Irradiation Reactions: Synthesis of Analgesic Drugs
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Abstract
Over-the-counter analgesics such as aspirin, acetanilide, phenacetin, and acetaminophen are conveniently prepared in a microwave at 30% power for five minutes. Recrystallization from appropriate solvents results in solid products in good to excellent yields. Melting points, thin layer chromatography, and infrared spectroscopy all confirm that the products are pure.
Keywords (Audience):
First-Year Undergraduate / GeneralKeywords (Domain):
Organic ChemistryKeywords (Pedagogy):
Hands-On Learning / ManipulativesKeywords (Subject):
Drugs / PharmaceuticalsCiting Articles
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This article has been cited by 14 ACS Journal articles (5 most recent appear below).
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Eric Martin and Cynthia Kellen-YuenJournal of Chemical Education2007 84 (12), 2004A greener, microwave-assisted Wittig reaction has been developed for the second-semester organic teaching laboratory. Utilizing this microwave technique, a variety of styrene derivatives have been successfully synthesized from aromatic aldehydes in good ...
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- Received: August 03, 2009
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