Blending in with the Body

Andrew L. Lewis and Mike Driver
Biocompatibles Ltd., Surrey GU9 8QL, England
J. Chem. Educ., 2002, 79 (3), p 321
DOI: 10.1021/ed079p321
Publication Date (Web): March 1, 2002
Pharmaceuticals

Abstract

Synthetic polymers based on naturally occurring phospholipid structures found in cell membranes are demonstrating significant clinical benefits in a number of application areas. The general synthesis and properties of materials in which the characterized feature is the presence of the phosphorylchloline group (PC) are described. Coatings and bulk materials containing PC markedly reduce the extent to which proteins adhere to their surface, which can result in improved acceptance by the body. The clinical merits of PC materials and coated devices used in the ocular and circulatory environments are discussed.

Keywords (Audience):

General Public

Keywords (Domain):

Biochemistry

Keywords (Feature):

Products of Chemistry

Keywords (Subject):

Lipids
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History

  • Received: August 03, 2009

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