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An Organic Puzzle Using Meldrum's Acid
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Abstract
Meldrum's acid or 2,2-dimethyl-1,3-dioxane-4,6-dione undergoes a Knoevenagel condensation with formaldehyde to form an active Michael acceptor for a second molecule of Meldrum's acid. The structure of the resulting product is determined by correlation of the products of possible reactions of Meldrum's acid and formaldehyde with the NMR spectrum of the product.
Keywords (Audience):
Second-Year UndergraduateKeywords (Domain):
Laboratory InstructionKeywords (Feature):
The Microscale LaboratoryKeywords (Pedagogy):
Problem Solving / Decision MakingKeywords (Subject):
NMR SpectroscopyCiting Articles
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This article has been cited by 6 ACS Journal articles (5 most recent appear below).
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- Received: August 03, 2009
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