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Aqueous-Phase Palladium-Catalyzed Coupling. A Green Chemistry Laboratory Experiment

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Brandy A. Harper , J. Chance Rainwater , Kurt Birdwhistell and D. Andrew Knight

Department of Chemistry, Loyola University, New Orleans, LA 70118

J. Chem. Educ., 2002, 79 (6), p 729

DOI: 10.1021/ed079p729

Publication Date (Web): June 1, 2002

Section:

History, Education, and Documentation

Abstract

An upper-level inorganic/organic experiment presents important concepts in modern green chemistry. A water-soluble modified triphenylphosphine ligand is prepared and used to prepare a water-soluble palladium catalyst. The palladium catalyst is formed in situ and used for the aqueous, homogenous, palladium-catalyzed cross-coupling reaction of iodobenzene and diethyl phosphite. The product is diethyl phenylphosphonate.

Keywords (Audience):

Upper-Division Undergraduate

Keywords (Domain):

Environmental Chemistry

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Catalysis

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This article has been cited by 11 ACS Journal articles (5 most recent appear below).

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