A Discovery Approach to Three Organic Laboratory Techniques: Extraction, Recrystallization, and Distillation

Gail Horowitz
Department of Chemistry, Yeshiva University, New York, NY 10033
J. Chem. Educ., 2003, 80 (9), p 1039
DOI: 10.1021/ed080p1039
Publication Date (Web): September 1, 2003

Abstract

This article describes three discovery-based experiments geared toward the beginning organic chemistry laboratory student. Each experiment focuses on one of the following purification techniques: extraction, recrystallization, or distillation. Unlike traditional purification-focused experiments whose goal is mastery of technique or optimization of results, the goal of these three experiments is students discovering for themselves the fundamental principles that underlie each technique. In each experiment, one or more parameters, such as solvent volume, time, or boiling point difference, is varied. Students compare the results of all variations and draw conclusions as to the underlying principles. The article concludes with an assessment of the effectiveness of these experiments.

Keywords (Audience):

Second-Year Undergraduate

Keywords (Domain):

Laboratory Instruction

Keywords (Pedagogy):

Collaborative / Cooperative Learning

Keywords (Subject):

Separation Science

Citing Articles

Citation data is made available by participants in CrossRef's Cited-by Linking service. For a more comprehensive list of citations to this article, users are encouraged to perform a search in SciFinder.

This article has been cited by 12 ACS Journal articles (5 most recent appear below).

  • Cover Image

    Ring-Closing Metathesis: An Advanced Guided-Inquiry Experiment for the Organic Laboratory

    Hala G. Schepmann and Michelle Mynderse
    Journal of Chemical Education2010 87 (7), 721-723
    • Ring-Closing Metathesis: An Advanced Guided-Inquiry Experiment for the Organic Laboratory

      Hala G. Schepmann and Michelle Mynderse
      Journal of Chemical Education2010 87 (7), 721-723

      The design and implementation of an advanced guided-inquiry experiment for the organic laboratory is described. Grubbs’s second-generation catalyst is used to effect the ring-closing metathesis of diethyl diallylmalonate. The reaction is carried out under ...

  • Cover Image

    A Forensic-Themed Case Study for the Organic Lab

    Kimberly Musa Specht , Michelle A. Boucher
    Journal of Chemical Education2009 86 (7), 847
    • A Forensic-Themed Case Study for the Organic Lab

      Kimberly Musa Specht , Michelle A. Boucher
      Journal of Chemical Education2009 86 (7), 847

      This laboratory study promotes student active-learning, engaging small groups of second-semester organic students with a "real-life" experience. The goal of this study is to have the students apply previously learned techniques to a forensic-case scenario ...

  • Cover Image

    A Discovery-Based Experiment Involving Rearrangement in the Conversion of Alcohols to Alkyl Halides

    Richard A. Kjonaas and Ryand J. F. Tucker
    Journal of Chemical Education2008 85 (1), 100
    • A Discovery-Based Experiment Involving Rearrangement in the Conversion of Alcohols to Alkyl Halides

      Richard A. Kjonaas and Ryand J. F. Tucker
      Journal of Chemical Education2008 85 (1), 100

      The use of permanent magnet 13C NMR in large-section first-semester organic chemistry lab courses is limited by the availability of experiments that not only hinge on first-semester lecture topics, but which also produce at least 0.5 mL of neat liquid ...

  • Cover Image

    A Guided-Inquiry Approach to the Sodium Borohydride Reduction and Grignard Reaction of Carbonyl Compounds

    Robert E. Rosenberg
    Journal of Chemical Education2007 84 (9), 1474
    • A Guided-Inquiry Approach to the Sodium Borohydride Reduction and Grignard Reaction of Carbonyl Compounds

      Robert E. Rosenberg
      Journal of Chemical Education2007 84 (9), 1474

      The guided-inquiry approach is applied to the reactions of sodium borohydride and phenyl magnesium bromide with benzaldehyde, benzophenone, benzoic anhydride, and ethyl benzoate. Each team of four students receives four unknowns. Students identify the ...

  • Cover Image

    The State of Organic Teaching Laboratories

    Gail Horowitz
    Journal of Chemical Education2007 84 (2), 346
    • The State of Organic Teaching Laboratories

      Gail Horowitz
      Journal of Chemical Education2007 84 (2), 346

      This review explores the dramatic changes that have taken place in the organic chemistry laboratory course over the last two to three decades. The most significant changes have been in the areas of pedagogy and technology. Significant inroads have been ...

Tools

SciFinder Links

SciFinder subscribers:  Click to sign in | Not a SciFinder subscriber? Learn more at www.cas.org

Explore by:


History

  • Received: August 03, 2009

Recommend & Share

  • Share on ACS NetworkACS Network
  • Add to FacebookFacebook
  • Tweet ThisTweet This
  • Add to CiteULikeCiteULike
  • Add to NewsvineNewsvine
  • Digg ThisDigg This
  • Add to DeliciousDelicious

Related Content

See also: