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The Bisphosphonate Story: From Detergents to Bone Disease

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Kathryn R. Williams

Department of Chemistry, University of Florida, Gainesville, FL 32611-7200

J. Chem. Educ., 2004, 81 (10), p 1406

DOI: 10.1021/ed081p1406

Publication Date (Web): October 1, 2004

Abstract

This offering From Past Issues discusses bisphosphonates and their intriguing history.

Keywords (Audience):

General Public

Keywords (Domain):

Biochemistry

Keywords (Feature):

From Past Issues

Keywords (Subject):

Aqueous Solution Chemistry

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This article has been cited by 1 ACS Journal articles (1 most recent appear below).

Ligand-Modified Aminobisphosphonate for Linking Proteins to Hydroxyapatite and Bone Surface
Robin S. Ehrick, Marcello Capaccio, David A. Puleo and Leonidas G. Bachas
Bioconjugate Chemistry2008 19 (1), 315-321
- Ligand-Modified Aminobisphosphonate for Linking Proteins to Hydroxyapatite and Bone Surface
  Robin S. Ehrick, Marcello Capaccio, David A. Puleo and Leonidas G. Bachas
  Bioconjugate Chemistry2008 19 (1), 315-321
  An increase in bone resorption is one of the main symptoms of osteoporosis, a disease that affects more and more individuals every day. Bisphosphonates are known to inhibit bone resorption and thus are being used as a treatment for osteoporosis. ...
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