Classroom Demonstration of a Spot Test for Phenylpyruvic Acid and Its Relationship to Phenylketonuria

Christopher J. Halkides
Department of Chemistry, University of North Carolina at Wilmington, Wilmington, NC 28403-5932
Kestas Benidinskas
Department of Chemistry, Kutztown University, Kutztown, PA 19530
J. Chem. Educ., 2004, 81 (3), p 366
DOI: 10.1021/ed081p366
Publication Date (Web): March 1, 2004

Abstract

A classroom demonstration of a spot test for phenylketonuria using ferric chloride is discussed. The chemistry is similar to that used in Phenistix test strips. Some background information on screening infants for phenylketonuria is also given.

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Keywords (Audience):

Upper-Division Undergraduate

Keywords (Domain):

Biochemistry

Keywords (Feature):

JCE DigiDemos: Tested Demonstrations

Keywords (Subject):

Amino Acids

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History

  • Received: August 03, 2009

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