Checkerboard Chromatography

Charles A. Smith
Department of Chemistry, Our Lady of the Lake University, San Antonio, TX 78207
J. Chem. Educ., 2004, 81 (3), p 384A
DOI: 10.1021/ed081p384A
Publication Date (Web): March 1, 2004

Abstract

This hands-on Activity allows students to simulate chromatographic simulations using a grid, colored pieces of paper, and a six-sided die. Students observe the separation as it is occurring and perform experiments on flow rate, column length, and mobile phase composition. This Activity is best performed after the class has discussed the topics of solubility and polarity. It can lead to discussions as to how separations are achieved in column chromatography. As the Activity progresses and students make observations, the instructor can introduce terminology including resolution, dead time, isocratic, gradient, and diffusion. The Activity is well suited for the high school or college level classroom where chromatographic concepts are being introduced.

Keywords (Audience):

High School / Introductory Chemistry

Keywords (Domain):

Analytical Chemistry

Keywords (Feature):

JCE Classroom Activity

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Chromatography

Citing Articles

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This article has been cited by 2 ACS Journal articles (2 most recent appear below).

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    Board-Game Gel Filtration and Affinity Chromatography

    Eric A. Hunt and Sapna K. Deo
    Journal of Chemical Education2009 86 (1), 19
    • Board-Game Gel Filtration and Affinity Chromatography

      Eric A. Hunt and Sapna K. Deo
      Journal of Chemical Education2009 86 (1), 19

      The gel filtration and affinity chromatography board game activity described here is a simulation of common chromatographic techniques. The game is suitable for use in a classroom or laboratory setting. This activity utilizes a paper grid, colored paper ...

  • Cover Image

    Connect the Dots

    Erica K. Jacobsen
    Journal of Chemical Education2008 85 (5), 605
    • Connect the Dots

      Erica K. Jacobsen
      Journal of Chemical Education2008 85 (5), 605

      Identifies and summarizes articles in this issue of the Journal that may be of particular interest to high school chemistry teachers.

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History

  • Received: August 03, 2009

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