Activity
Checkerboard Chromatography
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Abstract
This hands-on Activity allows students to simulate chromatographic simulations using a grid, colored pieces of paper, and a six-sided die. Students observe the separation as it is occurring and perform experiments on flow rate, column length, and mobile phase composition. This Activity is best performed after the class has discussed the topics of solubility and polarity. It can lead to discussions as to how separations are achieved in column chromatography. As the Activity progresses and students make observations, the instructor can introduce terminology including resolution, dead time, isocratic, gradient, and diffusion. The Activity is well suited for the high school or college level classroom where chromatographic concepts are being introduced.
Keywords (Audience):
High School / Introductory ChemistryKeywords (Domain):
Analytical ChemistryKeywords (Feature):
JCE Classroom ActivityKeywords (Pedagogy):
Hands-On Learning / ManipulativesKeywords (Subject):
ChromatographyCiting Articles
Citation data is made available by participants in CrossRef's Cited-by Linking service. For a more comprehensive list of citations to this article, users are encouraged to perform a search in SciFinder.
This article has been cited by 2 ACS Journal articles (2 most recent appear below).

Board-Game Gel Filtration and Affinity Chromatography
Eric A. Hunt and Sapna K. DeoJournal of Chemical Education2009 86 (1), 19Board-Game Gel Filtration and Affinity Chromatography
Eric A. Hunt and Sapna K. DeoJournal of Chemical Education2009 86 (1), 19The gel filtration and affinity chromatography board game activity described here is a simulation of common chromatographic techniques. The game is suitable for use in a classroom or laboratory setting. This activity utilizes a paper grid, colored paper ...

Connect the Dots
Erica K. JacobsenJournal of Chemical Education2008 85 (5), 605Connect the Dots
Erica K. JacobsenJournal of Chemical Education2008 85 (5), 605Identifies and summarizes articles in this issue of the Journal that may be of particular interest to high school chemistry teachers.
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History
- Received: August 03, 2009
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