Incorporation of Microwave Synthesis into the Undergraduate Organic Laboratory

E. Keller Barnhardt
Life Sciences Division, CEM Corporation, Matthews, NC 28106-0200
Alan R. Katritzky , Chunming Cai , Meghan D. Collins , Eric F. V. Scriven and Sandeep K. Singh
Department of Chemistry, University of Florida, Gainesville, FL 32611-7200
J. Chem. Educ., 2006, 83 (4), p 634
DOI: 10.1021/ed083p634
Publication Date (Web): April 1, 2006

Abstract

As the acceptance of microwave synthesis grows, it becomes increasingly important for undergraduate chemists to fully learn about this emerging technology. Advances have made microwave use in the undergraduate laboratory safe, easy, and affordable. Herein we describe a simple way to effectively implement microwave synthesis into the undergraduate organic laboratory curriculum.

Keywords (Audience):

First-Year Undergraduate / General

Keywords (Domain):

Laboratory Instruction

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Aromatic Compounds

Citing Articles

View all 10 citing articles

Citation data is made available by participants in CrossRef's Cited-by Linking service. For a more comprehensive list of citations to this article, users are encouraged to perform a search in SciFinder.

This article has been cited by 10 ACS Journal articles (5 most recent appear below).

  • Cover Image

    Metalloporphyrins as Oxidation Catalysts: Moving Toward “Greener” Chemistry in the Inorganic Chemistry Laboratory

    Rose A. Clark, Anne E. Stock, and Edward P. Zovinka
    Journal of Chemical Education2012 89 (2), 271-275
    • Metalloporphyrins as Oxidation Catalysts: Moving Toward “Greener” Chemistry in the Inorganic Chemistry Laboratory

      Rose A. Clark, Anne E. Stock, and Edward P. Zovinka
      Journal of Chemical Education2012 89 (2), 271-275

      Training future chemists to be aware of the environmental impact of their work is of fundamental importance to global society. To convince chemists to embrace sustainability, the integration of green chemistry across the entire chemistry curriculum is a ...

  • Cover Image

    Microwave-Assisted Synthesis of N-Phenylsuccinimide

    Thomas A. Shell, Jennifer R. Shell, Kathleen A. Poole, and Thomas F. Guetzloff
    Journal of Chemical Education2011 Article ASAP
    • Microwave-Assisted Synthesis of N-Phenylsuccinimide

      Thomas A. Shell, Jennifer R. Shell, Kathleen A. Poole, and Thomas F. Guetzloff
      Journal of Chemical Education2011 Article ASAP

      A microwave-assisted synthesis of N-phenylsuccinimide has been developed for the second-semester organic teaching laboratory. Utilizing this procedure, N-phenylsuccinimide can be synthesized in moderate yields (40–60%) by heating a mixture of aniline and ...

  • Cover Image

    Simple Microwave-Assisted Claisen and Dieckmann Condensation Experiments for the Undergraduate Organic Chemistry Laboratory

    Javier E. Horta
    Journal of Chemical Education2011 Article ASAP
    • Simple Microwave-Assisted Claisen and Dieckmann Condensation Experiments for the Undergraduate Organic Chemistry Laboratory

      Javier E. Horta
      Journal of Chemical Education2011 Article ASAP

      The Claisen condensation and its intramolecular variant the Dieckmann condensation are classic reactions studied in undergraduate organic chemistry courses because of their importance in organic synthesis and biochemical transformations. The growth in the ...

  • Cover Image

    Microwave Instruments: Green Machines for Green Chemistry?

    Edward P. Zovinka and Anne E. Stock
    Journal of Chemical Education2010 87 (4), 350-352
    • Microwave Instruments: Green Machines for Green Chemistry?

      Edward P. Zovinka and Anne E. Stock
      Journal of Chemical Education2010 87 (4), 350-352

      In this column, the authors discuss the ease of using microwave ovens for various activities in the undergraduate chemistry laboratory and suggest a few models of microwave systems for readers to consider.

  • Cover Image

    Greener Solutions for the Organic Chemistry Teaching Lab: Exploring the Advantages of Alternative Reaction Media

    Lallie C. McKenzie , Lauren M. Huffman and James E. Hutchison , Courtney E. Rogers and Thomas E. Goodwin , Gary O. Spessard
    Journal of Chemical Education2009 86 (4), 488
    • Greener Solutions for the Organic Chemistry Teaching Lab: Exploring the Advantages of Alternative Reaction Media

      Lallie C. McKenzie , Lauren M. Huffman and James E. Hutchison , Courtney E. Rogers and Thomas E. Goodwin , Gary O. Spessard
      Journal of Chemical Education2009 86 (4), 488

      A major approach for implementing green chemistry is the discovery and development of synthetic strategies that reduce the quantity of solvent needed, eliminate it altogether, or rely on new reaction media. An increasing number of examples have ...

Tools

SciFinder Links

SciFinder subscribers:  Click to sign in | Not a SciFinder subscriber? Learn more at www.cas.org

Explore by:


History

  • Received: August 03, 2009

Recommend & Share

  • Share on ACS NetworkACS Network
  • Add to FacebookFacebook
  • Tweet ThisTweet This
  • Add to CiteULikeCiteULike
  • Add to NewsvineNewsvine
  • Digg ThisDigg This
  • Add to DeliciousDelicious

Related Content