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A Quick and Easy Simplification of Benzocaine's NMR Spectrum

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Suzanne R. Carpenter and Richard H. Wallace

Department of Chemistry and Physics, Armstrong Atlantic State University, Savannah, GA 31419

J. Chem. Educ., 2006, 83 (4), p 637

DOI: 10.1021/ed083p637

Publication Date (Web): April 1, 2006

Section:

History, Education, and Documentation

Abstract

The preparation of benzocaine is a common experiment used in sophomore-level organic chemistry. Its straightforward procedure and predictable good yields make it ideal for the beginning organic student. Analysis of the product via NMR spectroscopy, however, can be confusing to the novice interpreter. An inexpensive, quick, and effective method for simplifying the NMR spectrum is reported. The method results in a spectrum that is cleanly integrated and more easily interpreted.

Keywords (Audience):

Second-Year Undergraduate

Keywords (Domain):

Laboratory Instruction

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Drugs / Pharmaceuticals

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Received: August 03, 2009

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A Quick and Easy Simplification of Benzocaine's NMR Spectrum