Using an NMR Spectrometer To Do Magnetic Resonance Imaging

Wayne E. Steinmetz and M. Cyrus Maher
Department of Chemistry, Pomona College, Claremont, CA 91711
J. Chem. Educ., 2007, 84 (11), p 1830
DOI: 10.1021/ed084p1830
Publication Date (Web): November 1, 2007
History, Education, and Documentation

Abstract

A conventional Fourier-transform NMR spectrometer with a triple-axis gradient probe can function as a MRI imager. In this experiment students gain hands-on experience with MRI while they learn about important principles underlying the practice of NMR, such as gradients, multi-dimensional spectroscopy, and relaxation. Students image a biological specimen that fits in a 5-mm NMR tube with the multi-slice-multi-echo (MSME) method and measure the transverse relaxation time, T2, of water in selected regions of interest.

Keywords (Audience):

Upper-Division Undergraduate

Keywords (Domain):

Laboratory Instruction

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Biophysical Chemistry
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  • Received: August 03, 2009

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