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Introduction to Protein Structure through Genetic Diseases
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Abstract
An illuminating way to learn about protein function is to explore high-resolution protein structures. Analysis of the proteins involved in genetic diseases has been used to introduce students to protein structure and the role that individual mutations can play in the onset of disease. Known mutations can be correlated to changes in protein activity, structure, or processing. Students gain the skills to manipulate high-resolution protein structures and an understanding of how structural changes can lead to disease.
Keywords (Audience):
Upper-Division UndergraduateKeywords (Domain):
BiochemistryKeywords (Pedagogy):
Computer-Based LearningKeywords (Subject):
EnzymesCiting Articles
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This article has been cited by 1 ACS Journal articles (1 most recent appear below).

“Design Your Own Disease” Assignment: Teaching Students To Apply Metabolic Pathways
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Nick FlynnJournal of Chemical Education2010 87 (8), 799-802One of the major focuses of biochemistry courses is metabolic pathways. Although certain aspects of this content may require a rote approach, more applied techniques make these subject areas more interesting. This article describes the use of an ...
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History
- Received: August 03, 2009
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