Using Laboratory Chemicals To Imitate Illicit Drugs in a Forensic Chemistry Activity

Shawn Hasan , Deborah Bromfield-Lee , Maria T. Oliver-Hoyo and Jose A. Cintron-Maldonado
Department of Chemistry, North Carolina State University, Raleigh, NC 27695
J. Chem. Educ., 2008, 85 (6), p 813
DOI: 10.1021/ed085p813
Publication Date (Web): June 1, 2008

Abstract

This forensic chemistry activity utilizes presumptive forensic testing procedures and laboratory chemicals that produce screening results similar to controlled substances. For obvious reasons, obtaining heavily regulated controlled substances to create an undergraduate student activity is not practical for most educational institutions. We were able to identify over-the-counter and laboratory chemicals that mimic actual street drugs in terms of physical properties and color response. Using these selected chemicals, the screening aspect of drug testing provides students with the opportunity to understand what obstacles a forensic chemist faces when analyzing a sample of unknown identity. Chemical spot tests (CSTs) and thin-layer chromatography (TLC) were chosen owing to their simplicity, versatility, common use by forensic chemists, availability, and cost of the reagents and equipment needed. Students are expected to explain how simple color reactions can screen for illicit drugs, to describe how TLC can be used to separate and tentatively identify drugs, to predict how polarity changes affect TLC results, and to explain why CSTs and TLC serve for screening purposes only.

Keywords (Audience):

First-Year Undergraduate / General

Keywords (Domain):

Analytical Chemistry

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Applications of Chemistry

Citing Articles

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This article has been cited by 4 ACS Journal articles (4 most recent appear below).

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    Molecular Models of Real and Mock Illicit Drugs from a Forensic Chemistry Activity

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    • Molecular Models of Real and Mock Illicit Drugs from a Forensic Chemistry Activity

      William F. Coleman
      Journal of Chemical Education2008 85 (6), 880

      The Featured Molecules for this month have been drawn from a forensic chemistry exercise in which model compounds are used to simulate the behavior of various drugs in a series of chemical tests. The compounds considered include chlorpromazine (Thorazine) ...

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History

  • Received: August 03, 2009

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