Magnetic Field Gradient Calibration as an Experiment To Illustrate Magnetic Resonance Imaging

Steven J. Seedhouse and Markus M. Hoffmann
Department of Chemistry, State University of New York College at Brockport, Brockport, NY 14420
J. Chem. Educ., 2008, 85 (6), p 836
DOI: 10.1021/ed085p836
Publication Date (Web): June 1, 2008

Abstract

A nuclear magnetic resonance (NMR) spectroscopy experiment for the undergraduate physical chemistry laboratory is described that encompasses both qualitative and quantitative pedagogical goals. Qualitatively, the experiment illustrates how images are obtained in magnetic resonance imaging (MRI). Quantitatively, students experience the relationships between gradient strength, spectral width, and the quality of the obtained projection images as they calibrate the maximum field gradient strength of the instrument. They also find out the size of a trapped air bubble in their sample in close analogy how one could obtain information on physical sizes of objects in MRI.

Keywords (Audience):

Upper-Division Undergraduate

Keywords (Domain):

Laboratory Instruction

Keywords (Pedagogy):

Hands-On Learning / Manipulatives

Keywords (Subject):

Calibration

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This article has been cited by 1 ACS Journal articles (1 most recent appear below).

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    Supramolecular Assemblies of Histidinylated α-Cyclodextrin in the Presence of DNA Scaffold during CDplexes Formation

    Véronique Bennevault-Celton, Allan Urbach, Olivier Martin, Chantal Pichon, Philippe Guégan, and Patrick Midoux
    Bioconjugate Chemistry2011 22 (12), 2404-2414
    • Supramolecular Assemblies of Histidinylated α-Cyclodextrin in the Presence of DNA Scaffold during CDplexes Formation

      Véronique Bennevault-Celton, Allan Urbach, Olivier Martin, Chantal Pichon, Philippe Guégan, and Patrick Midoux
      Bioconjugate Chemistry2011 22 (12), 2404-2414

      α-Cyclodextrin was transformed in a cationic unit after per substitution with histidine (His-α-CD) and lysine (Lys-α-CD) molecules on the primary face. His-α-CD and Lys-α-CD were used to form electrostatic complexes (CDplexes) with a plasmid DNA encoding ...

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History

  • Received: August 03, 2009

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