Chronology of a Difficult Synthesis

Fredric M. Menger and Jennifer L. Sorrells
Department of Chemistry, Emory University, Atlanta, GA 30322
J. Chem. Educ., 2009, 86 (7), p 859
DOI: 10.1021/ed086p859
Publication Date (Web): July 1, 2009

Abstract

This article describes a short synthesis and many of the difficulties experienced while carrying it out (e.g., low yields, impurities, racemization, nonrepeatable literature preps, etc.). As such, students will be educated in aspects of synthetic organic chemistry that are often down-played, or even not mentioned, in published syntheses.

Keywords (Audience):

Upper-Division Undergraduate

Keywords (Domain):

Laboratory Instruction

Keywords (Feature):

Research: Science and Education

Keywords (Pedagogy):

Problem Solving / Decision Making

Keywords (Subject):

Descriptive Chemistry

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This article has been cited by 1 ACS Journal articles (1 most recent appear below).

  • Cover Image

    Remembrances of Self-Assemblies Past

    Fredric M. Menger
    Langmuir2011 27 (9), 5176-5183
    • Remembrances of Self-Assemblies Past

      Fredric M. Menger
      Langmuir2011 27 (9), 5176-5183

      Research on four types of self-assemblies (micelles, coacervates, gels, and vesicles) is discussed via a particular investigative methodology (in order of appearance): kinetics, dynamic NMR, PGSE-NMR, double-13C labeling, molecular dynamics computations, ...

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History

  • Received: August 03, 2009

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