Cart
Article
Synthesis and Characterization of Cross-Bridged Cyclams and Pendant-Armed Derivatives and Structural Studies of Their Copper(II) Complexes
Full Text HTML
Hi-Res PDFPurchase the full-text
- PDF/HTML,
figures/images,
references and tables,
(where available)
Mark E. Rogers,† Jeffrey S. Condon,† Maureen A. Fagan,†
Joseph C. Calabrese,‡ Kin-Chung Lam,§ Ilia A. Guzei,§# and Arnold L. Rheingold§
Section:Abstract
A series of 1,4,8,11-tetraazabicyclo[6.6.2]hexadecane ligands, including the parent compound, N,N‘-dialkyl variants, and the first N,N‘-di-pendant-arm derivatives have been synthesized by a short, efficient, and conceptually novel approach. Their copper(II) complexes have been prepared, and four of these were structurally characterized by X-ray diffraction. In all four complexes, the cross-bridged tetraamine ligand was found to be cis-folded, coordinating the metal cation within its molecular cleft using all four nitrogen lone pairs. Geometries intermediate between idealized square pyramidal and trigonal bipyramidal coordination were found for three of the complexes, whereas a distorted octahedral copper coordination was found for the complex of a di-pendant-arm cross-bridged cyclam.
Citing Articles
Citation data is made available by participants in CrossRef's Cited-by Linking service. For a more comprehensive list of citations to this article, users are encouraged to perform a search in SciFinder.
This article has been cited by 17 ACS Journal articles (5 most recent appear below).
Isomeric Trimethylene and Ethylene Pendant-armed Cross-bridged Tetraazamacrocycles and in Vitro/in Vivo Comparisions of their Copper(II) Complexes
Antoinette Y. Odendaal, Ashley L. Fiamengo, Riccardo Ferdani, Thaddeus J. Wadas, Daniel C. Hill, Yijie Peng, Katie J. Heroux, James A. Golen, Arnold L. Rheingold, Carolyn J. Anderson, Gary R. Weisman, and Edward H. WongInorganic Chemistry2011 50 (7), 3078-3086Isomeric Trimethylene and Ethylene Pendant-armed Cross-bridged Tetraazamacrocycles and in Vitro/in Vivo Comparisions of their Copper(II) Complexes
Antoinette Y. Odendaal, Ashley L. Fiamengo, Riccardo Ferdani, Thaddeus J. Wadas, Daniel C. Hill, Yijie Peng, Katie J. Heroux, James A. Golen, Arnold L. Rheingold, Carolyn J. Anderson, Gary R. Weisman, and Edward H. WongInorganic Chemistry2011 50 (7), 3078-3086Ethylene cross-bridged tetraamine macrocycles are useful chelators in coordination, catalytic, medicinal, and radiopharmaceutical chemistry. Springborg and co-workers developed trimethylene cross-bridged analogues, although their pendant-armed derivatives ...
Liposomal Cu-64 Labeling Method Using Bifunctional Chelators: Poly(ethylene glycol) Spacer and Chelator Effects
Jai Woong Seo, Lisa M. Mahakian, Azadeh Kheirolomoom, Hua Zhang, Claude F. Meares, Riccardo Ferdani, Carolyn J. Anderson and Katherine W. FerraraBioconjugate Chemistry2010 21 (7), 1206-1215Liposomal Cu-64 Labeling Method Using Bifunctional Chelators: Poly(ethylene glycol) Spacer and Chelator Effects
Jai Woong Seo, Lisa M. Mahakian, Azadeh Kheirolomoom, Hua Zhang, Claude F. Meares, Riccardo Ferdani, Carolyn J. Anderson and Katherine W. FerraraBioconjugate Chemistry2010 21 (7), 1206-1215Two bifunctional Cu-64 chelators (BFCs), (6-(6-(3-(2-pyridyldithio)propionamido)hexanamido)benzyl)-1,4,8,11-tetraazacyclotetradecane-1,4,8,11-tetraacetic acid (TETA-PDP) and 4-(2-(2-pyridyldithioethyl)ethanamido)-11-carboxymethyl-1,4,8,11-tetraazabicyclo(...
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
Thaddeus J. Wadas, Edward H. Wong, Gary R. Weisman and Carolyn J. AndersonChemical Reviews2010 110 (5), 2858-2902Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
Thaddeus J. Wadas, Edward H. Wong, Gary R. Weisman and Carolyn J. AndersonChemical Reviews2010 110 (5), 2858-2902
Molecular Imaging of Cancer with Copper-64 Radiopharmaceuticals and Positron Emission Tomography (PET)
Monica Shokeen and Carolyn J. AndersonAccounts of Chemical Research2009 42 (7), 832-841Molecular Imaging of Cancer with Copper-64 Radiopharmaceuticals and Positron Emission Tomography (PET)
Monica Shokeen and Carolyn J. AndersonAccounts of Chemical Research2009 42 (7), 832-841Molecular imaging has evolved over the past several years into an important tool for diagnosing, understanding, and monitoring disease. Molecular imaging has distinguished itself as an interdisciplinary field, with contributions from chemistry, biology, ...
Understanding Atom Transfer Radical Polymerization: Effect of Ligand and Initiator Structures on the Equilibrium Constants
Wei Tang, Yungwan Kwak, Wade Braunecker, Nicolay V. Tsarevsky, Michelle L. Coote and Krzysztof MatyjaszewskiJournal of the American Chemical Society2008 130 (32), 10702-10713Understanding Atom Transfer Radical Polymerization: Effect of Ligand and Initiator Structures on the Equilibrium Constants
Wei Tang, Yungwan Kwak, Wade Braunecker, Nicolay V. Tsarevsky, Michelle L. Coote and Krzysztof MatyjaszewskiJournal of the American Chemical Society2008 130 (32), 10702-10713Equilibrium constants in Cu-based atom transfer radical polymerization (ATRP) were determined for a wide range of ligands and initiators in acetonitrile at 22 °C. The ATRP equilibrium constants obtained vary over 7 orders of magnitude and strongly depend ...
Tools
-
Add to Favorites
-
Download Citation
-
Email a Colleague -
Permalink
Order Reprints
Rights & Permissions
Citation Alerts
History
- Published In Issue November 01, 2000
- Received April 13, 2000
ACS
Network
Facebook
Tweet This
CiteULike
Newsvine
Digg This
Delicious
