Biomimetic Total Syntheses of (+)-Cephalostatin 7, (+)-Cephalostatin 12, and (+)-Ritterazine K

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• Interphylal Product Splicing:  The First Total Syntheses of Cephalostatin 1, the North Hemisphere of Ritterazine G, and the Highly Active Hybrid Analogue, Ritterostatin G_N1_N¹Journal of the American Chemical Society

  • Interphylal Product Splicing:  The First Total Syntheses of Cephalostatin 1, the North Hemisphere of Ritterazine G, and the Highly Active Hybrid Analogue, Ritterostatin G_N1_N¹

    Thomas G. LaCour, Chuangxing Guo, Sudhakar Bhandaru, Michael R. Boyd, and P. L. Fuchs
    Journal of the American Chemical Society 1998 120 (4), pp 692–707

    Abstract: Convergent total syntheses of the extremely potent cell growth inhibitor cephalostatin 1 and two hybrid analogues, ritterostatins G_N1_N and G_N1_S, have been achieved. Ritterostatin G_N1_N displays sub-nanomolar activity in the 60 cell line human tumor panel ...

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Other ACS content by these authors:

• Jae Uk Jeong
• Scott C. Sutton
• Seongkon Kim
• P. L. Fuchs