The Guanacastepenes:  A Highly Diverse Family of Secondary Metabolites Produced by an Endophytic Fungus

Related Content

• Guanacastepene, a Fungal-Derived Diterpene Antibiotic with a New Carbon SkeletonJournal of the American Chemical Society

  • Guanacastepene, a Fungal-Derived Diterpene Antibiotic with a New Carbon Skeleton

    Sean F. Brady, Maya P. Singh, Jeff E. Janso, and Jon Clardy
    Journal of the American Chemical Society 2000 122 (9), pp 2116–2117
    Abstract | Full Text HTML | Hi-Res PDF
• Electrostatic Effects on the Reactions of Cyclohexanone Oxocarbenium IonsThe Journal of Organic Chemistry

  • Electrostatic Effects on the Reactions of Cyclohexanone Oxocarbenium Ions

    Glen Baghdasarian and K. A. Woerpel
    The Journal of Organic Chemistry 2006 71 (18), pp 6851–6858

    Abstract: Nucleophilic substitution reactions of 4-substituted cyclohexanone acetals display different selectivities depending upon the electronic nature of the substituent. Alkyl groups favor equatorial positions in the oxocarbenium ions, but alkoxy groups prefer ...

    Abstract | Full Text HTML | Hi-Res PDF
• Dramatic Switching of Protein Kinase C Agonist/Antagonist Activity by Modifying the 12-Ester Side Chain of Phorbol EstersJournal of the American Chemical Society

  • Dramatic Switching of Protein Kinase C Agonist/Antagonist Activity by Modifying the 12-Ester Side Chain of Phorbol Esters

    Reiko Wada, Yutaka Suto, Motomu Kanai, and Masakatsu Shibasaki
    Journal of the American Chemical Society 2002 124 (36), pp 10658–10659

    Abstract: A dramatic switching of PKC agonist and antagonist activity was observed by modification of the hydrophilicity of the 12-ester side chain of phorbol. Thus, phorbol ester 4 that contains a glycol at the 12-ester chain demonstrated a pure and significant ...

    Abstract | Full Text HTML | Hi-Res PDF

Other ACS content by these authors:

• Sean F. Brady
• Shana M. Bondi
• Jon Clardy