Label-Free Electronic Detection of DNA-Hybridization on Nanogapped Gold Particle Film

Hiroshi Shiigi, Shiho Tokonami, Hidetaka Yakabe, and Tsutomu Nagaoka*
Research Institute of Advanced Science & Technology, Osaka Prefecture University, 1-2 Gakuen, Sakai 599-8570, Japan, and Faculty of Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube 755-8611, Japan
J. Am. Chem. Soc., 2005, 127 (10), pp 3280–3281
DOI: 10.1021/ja0445793
Publication Date (Web): February 17, 2005
Copyright © 2005 American Chemical Society

 Osaka Prefecture University.

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 Yamaguchi University.

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*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, nagaoka@riast.osakafu-u.ac.jp

Abstract

Abstract Image

A label-free high-resolution DNA sensing technique using a nanogapped gold particle film is presented to acquire nucleotide polymorphism information, which can be read by electronic protocols.

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History

  • Published In Issue March 16, 2005
  • Received September 8, 2004

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