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Communication

CuBr-Catalyzed Efficient Alkynylation of sp³ C−H Bonds Adjacent to a Nitrogen Atom

Supporting Info

Zhiping Li and Chao-Jun Li*

Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 2K6, Canada

J. Am. Chem. Soc., 2004, 126 (38), pp 11810–11811

DOI: 10.1021/ja0460763

Publication Date (Web): September 2, 2004

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, cj.li@mcgill.ca

Abstract

A simple and effective catalytic method to construct propargylamine was developed by using copper bromide and tert-BuOOH via a combination of sp³ C−H bond and sp C−H bond activations followed by C−C bond formation.

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Published In Issue September 29, 2004
Received July 1, 2004

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Communication

CuBr-Catalyzed Efficient Alkynylation of sp³ C−H Bonds Adjacent to a Nitrogen Atom