Iron-Catalyzed Cross-Coupling of Primary and Secondary Alkyl Halides with Aryl Grignard Reagents

Masaharu Nakamura,* Keiko Matsuo, Shingo Ito, and Eiichi Nakamura*;
Department of Chemistry, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
J. Am. Chem. Soc., 2004, 126 (12), pp 3686–3687
DOI: 10.1021/ja049744t
Publication Date (Web): March 4, 2004
Copyright © 2004 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

,

 PRESTO, Japan Science and Technology Agency (JST).

, masaharu@chem.s.u-tokyo.ac.jp, ; , nakamura@chem.s.u-tokyo.ac.jp

Abstract

Abstract Image

An iron-catalyzed cross-coupling reaction of a primary or secondary alkyl halide with an aryl Grignard reagent proceeds under mild conditions to give the corresponding coupling product in quantitative yield.

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History

  • Published In Issue March 31, 2004
  • Received January 15, 2004

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