Cart
Article
A Europium Complex That Selectively Stains Nucleoli of Cells
Full Text HTML
Hi-Res PDFPurchase the full-text
- PDF/HTML,
figures/images,
references and tables,
(where available)
Section:Abstract
A europium complex selectively staining the nucleolus of NIH 3T3, HeLa, and HDF cells is reported. This complex possesses not only the advantage of the long lifetime of europium emission (0.3 ms), but also a chromophore that allows excitation at a relatively long wavelength (λmax = 384 nm) and gives rise to an acceptable quantum yield (9%). The complex can be used both in live cell and fixed cell imaging, giving an average intracellular concentration on the order of 0.5 μM. Strong binding to serum albumin has been demonstrated by examination of the analogous gadolinium complex, studying relaxivity changes with increasing protein concentration. The intracellular speciation of the complex has been examined by circularly polarized emission spectroscopy and is consistent with the presence of more than one europium species, possibly protein bound.
Citing Articles
Citation data is made available by participants in CrossRef's Cited-by Linking service. For a more comprehensive list of citations to this article, users are encouraged to perform a search in SciFinder.
This article has been cited by 27 ACS Journal articles (5 most recent appear below).
Water-Soluble Mitochondria-Specific Ytterbium Complex with Impressive NIR Emission
Tao Zhang, Xunjin Zhu, Chopen C. W. Cheng, Wai-Ming Kwok, Hoi-Lam Tam, Jianhua Hao, Daniel W. J. Kwong, Wai-Kwok Wong, and Ka-Leung WongJournal of the American Chemical Society2011 133 (50), 20120-20122Water-Soluble Mitochondria-Specific Ytterbium Complex with Impressive NIR Emission
Tao Zhang, Xunjin Zhu, Chopen C. W. Cheng, Wai-Ming Kwok, Hoi-Lam Tam, Jianhua Hao, Daniel W. J. Kwong, Wai-Kwok Wong, and Ka-Leung WongJournal of the American Chemical Society2011 133 (50), 20120-20122A water-soluble porphyrinato ytterbium complex linked with rhodamine B (Yb-2) showed mitochondria-specific subcellular localization and strong two-photon-induced NIR emissions (λem = 650 nm, porphyrinate ligand π → π* transition; λem = 1060 nm, Yb(III) 5F...
A Nonemissive Iridium(III) Complex That Specifically Lights-Up the Nuclei of Living Cells
Chunyan Li, Mengxiao Yu, Yun Sun, Yongquan Wu, Chunhui Huang, and Fuyou LiJournal of the American Chemical Society2011 133 (29), 11231-11239A Nonemissive Iridium(III) Complex That Specifically Lights-Up the Nuclei of Living Cells
Chunyan Li, Mengxiao Yu, Yun Sun, Yongquan Wu, Chunhui Huang, and Fuyou LiJournal of the American Chemical Society2011 133 (29), 11231-11239A nonemissive cyclometalated iridium(III) solvent complex, without conjugation with a cell-penetrating molecular transporter, [Ir(ppy)2(DMSO)2]+PF6– (LIr1), has been developed as a first reaction-based fluorescence-turn-on agent for the nuclei of living ...
Noncovalent Ligand-to-Ligand Interactions Alter Sense of Optical Chirality in Luminescent Tris(β-diketonate) Lanthanide(III) Complexes Containing a Chiral Bis(oxazolinyl) Pyridine Ligand
Junpei Yuasa, Tomoko Ohno, Kohei Miyata, Hiroyuki Tsumatori, Yasuchika Hasegawa, and Tsuyoshi KawaiJournal of the American Chemical Society2011 133 (25), 9892-9902Noncovalent Ligand-to-Ligand Interactions Alter Sense of Optical Chirality in Luminescent Tris(β-diketonate) Lanthanide(III) Complexes Containing a Chiral Bis(oxazolinyl) Pyridine Ligand
Junpei Yuasa, Tomoko Ohno, Kohei Miyata, Hiroyuki Tsumatori, Yasuchika Hasegawa, and Tsuyoshi KawaiJournal of the American Chemical Society2011 133 (25), 9892-9902Highly luminescent tris[β-diketonate (HFA, 1,1,1,5,5,5-hexafluoropentane-2,4-dione)] europium(III) complexes containing a chiral bis(oxazolinyl) pyridine (pybox) ligand—[(EuIII(R)-Ph-pybox)(HFA)3], [(EuIII(R)-i-Pr-pybox)(HFA)3], and [(EuIII(R)-Me-Ph-pybox)...
Photoluminescent Lanthanide-Doped Silica Nanotubes: Sol−Gel Transcription from Functional Template
Yan Qiao, Huanfa Chen, Yiyang Lin, Zhiyi Yang, Xinhao Cheng, and Jianbin HuangThe Journal of Physical Chemistry C2011 115 (15), 7323-7330Photoluminescent Lanthanide-Doped Silica Nanotubes: Sol−Gel Transcription from Functional Template
Yan Qiao, Huanfa Chen, Yiyang Lin, Zhiyi Yang, Xinhao Cheng, and Jianbin HuangThe Journal of Physical Chemistry C2011 115 (15), 7323-7330Functional photoluminescent materials have emerged as a fascinating research subject holding great promise in versatile applications. In this report, photoluminescent lanthanide-organic hybrid nanofibers in hydrogels are fabricated through supramolecular ...
Luminescent Rare-Earth Complex Covalently Modified Single-Walled Carbon Nanotubes: Design, Synthesis, and DNA Sequence-Dependent Red Luminescence Enhancement
Chao Zhao, Yujun Song, Konggang Qu, Jinsong Ren, and Xiaogang QuChemistry of Materials2010 22 (20), 5718-5724Luminescent Rare-Earth Complex Covalently Modified Single-Walled Carbon Nanotubes: Design, Synthesis, and DNA Sequence-Dependent Red Luminescence Enhancement
Chao Zhao, Yujun Song, Konggang Qu, Jinsong Ren, and Xiaogang QuChemistry of Materials2010 22 (20), 5718-5724A novel luminescent Eu3+-complex functionalized single-walled carbon nanotube (SWNT) was constructed by covalent linkage through a diaminotriethylene glycol linker. TGA, FT-IR, and SEM demonstrated successful attachment of the Eu3+-complex onto the SWNT ...
Tools
-
Add to Favorites
-
Download Citation
-
Email a Colleague -
Permalink
Order Reprints
Rights & Permissions
Citation Alerts
History
- Published In Issue February 22, 2006
- Received September 13, 2005
ACS
Network
Facebook
Tweet This
CiteULike
Newsvine
Digg This
Delicious
