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Communication

Controlling Regiochemistry in Negishi Carboaluminations. Fine Tuning the Ligand on Zirconium

Supporting Info

Bruce H. Lipshutz,* Tom Butler, and Asher Lower

Department of Chemistry & Biochemistry, University of California, Santa Barbara, California 93106

J. Am. Chem. Soc., 2006, 128 (48), pp 15396–15398

DOI: 10.1021/ja065769b

Publication Date (Web): November 9, 2006

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, lipshutz@chem.ucsb.edu

Abstract

The species on the zirconocene catalyst is changed from two Cp's to the Brintzinger ligand and catalytic amounts of MAO are used to usually effect a >99% regiocontrol of Negishi carboaluminations of 1-alkynes in toluene.

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Published In Issue December 06, 2006
Received August 8, 2006

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Communication

Controlling Regiochemistry in Negishi Carboaluminations. Fine Tuning the Ligand on Zirconium

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Multiple Mechanistic Pathways for Zirconium-Catalyzed Carboalumination of Alkynes. Requirements for Cyclic Carbometalation Processes Involving C−H Activation

Enantiospecific Total Syntheses of Kapakahines B and F

Enantioselective Total Synthesis of (−)-Napyradiomycin A1 via Asymmetric Chlorination of an Isolated Olefin

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