Inhibition of Pseudomonas aeruginosa Biofilm Formation with Bromoageliferin Analogues

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79. Steven A. Rogers, Erick A. Lindsey, Daniel C. Whitehead, Trey Mullikin, Christian Melander. Synthesis and biological evaluation of 2-aminoimidazole/carbamate hybrid anti-biofilm and anti-microbial agents. Bioorganic & Medicinal Chemistry Letters 2011, 21 (4) , 1257-1260. https://doi.org/10.1016/j.bmcl.2010.12.057
80. Lindsay Kalan, Gerard D. Wright. Antibiotic adjuvants: multicomponent anti-infective strategies. Expert Reviews in Molecular Medicine 2011, 13 https://doi.org/10.1017/S1462399410001766
81. Kelly C. Peach, Walter M. Bray, Nicholas J. Shikuma, Nadine C. Gassner, R. Scott Lokey, Fitnat H. Yildiz, Roger G. Linington. An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae. Molecular BioSystems 2011, 7 (4) , 1176. https://doi.org/10.1039/c0mb00276c
82. Ali Al-Mourabit, Manuel A. Zancanella, Supriya Tilvi, Daniel Romo. Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids. Natural Product Reports 2011, 28 (7) , 1229. https://doi.org/10.1039/c0np00013b
83. Samuel Reyes, Robert W. Huigens III, Zhaoming Su, Michel L. Simon, Christian Melander. Synthesis and biological activity of 2-aminoimidazole triazoles accessed by Suzuki–Miyaura cross-coupling. Organic & Biomolecular Chemistry 2011, 9 (8) , 3041. https://doi.org/10.1039/c0ob00925c
84. Denis S. Ermolat'ev, Jitender B. Bariwal, Hans P. L. Steenackers, Sigrid C. J. De Keersmaecker, Erik V. Van der Eycken. Concise and Diversity‐Oriented Route toward Polysubstituted 2‐Aminoimidazole Alkaloids and Their Analogues. Angewandte Chemie International Edition 2010, 49 (49) , 9465-9468. https://doi.org/10.1002/anie.201004256
85. Denis S. Ermolat'ev, Jitender B. Bariwal, Hans P. L. Steenackers, Sigrid C. J. De Keersmaecker, Erik V. Van der Eycken. Concise and Diversity-Oriented Route toward Polysubstituted 2-Aminoimidazole Alkaloids and Their Analogues. Angewandte Chemie 2010, 122 (49) , 9655-9658. https://doi.org/10.1002/ange.201004256
86. Cynthia A. Bunders, Justin J. Richards, Christian Melander. Identification of aryl 2-aminoimidazoles as biofilm inhibitors in Gram-negative bacteria. Bioorganic & Medicinal Chemistry Letters 2010, 20 (12) , 3797-3800. https://doi.org/10.1016/j.bmcl.2010.04.042
87. S. A. Rogers, R. W. Huigens, J. Cavanagh, C. Melander. Synergistic Effects between Conventional Antibiotics and 2-Aminoimidazole-Derived Antibiofilm Agents. Antimicrobial Agents and Chemotherapy 2010, 54 (5) , 2112-2118. https://doi.org/10.1128/AAC.01418-09
88. Dinty J. Musk. Zinc Fingered: New Compounds that Thwart Gram‐Positive Biofilm Formation by Sequestering Zinc. ChemBioChem 2010, 11 (6) , 758-760. https://doi.org/10.1002/cbic.200900691
89. Katherine M. Schmalzer, Marc A. Benson, Dara W. Frank. Activation of ExoU Phospholipase Activity Requires Specific C-Terminal Regions. Journal of Bacteriology 2010, 192 (7) , 1801-1812. https://doi.org/10.1128/JB.00904-09
90. Steven A. Rogers, Joseph D. Bero, Christian Melander. Chemical Synthesis and Biological Screening of 2‐Aminoimidazole‐Based Bacterial and Fungal Antibiofilm Agents. ChemBioChem 2010, 11 (3) , 396-410. https://doi.org/10.1002/cbic.200900617
91. Robert W. Huigens, Samuel Reyes, Catherine S. Reed, Cynthia Bunders, Steven A. Rogers, Andrew T. Steinhauer, Christian Melander. The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. Bioorganic & Medicinal Chemistry 2010, 18 (2) , 663-674. https://doi.org/10.1016/j.bmc.2009.12.003
92. Zhaoming Su, Steven A. Rogers, W. Steve McCall, Alicia C. Smith, Sindhu Ravishankar, Trey Mullikin, Christian Melander. A nitroenolate approach to the synthesis of 4,5-disubstituted-2-aminoimidazoles. Pilot library assembly and screening for antibiotic and antibiofilm activity. Organic & Biomolecular Chemistry 2010, 8 (12) , 2814. https://doi.org/10.1039/c001479f
93. Steven A. Rogers, Daniel C. Whitehead, Trey Mullikin, Christian Melander. Synthesis and bacterial biofilm inhibition studies of ethyl N-(2-phenethyl) carbamate derivatives. Organic & Biomolecular Chemistry 2010, 8 (17) , 3857. https://doi.org/10.1039/c0ob00063a
94. Barbara Forte, Beatrice Malgesini, Claudia Piutti, Francesca Quartieri, Alessandra Scolaro, Gianluca Papeo. A Submarine Journey: The Pyrrole-Imidazole Alkaloids. Marine Drugs 2009, 7 (4) , 705-753. https://doi.org/10.3390/md7040705
95. Justin J. Richards, Christian Melander. Controlling Bacterial Biofilms. ChemBioChem 2009, 10 (14) , 2287-2294. https://doi.org/10.1002/cbic.200900317
96. Jeffrey L. Veesenmeyer, Alan R. Hauser, Thiago Lisboa, Jordi Rello. Pseudomonas aeruginosa virulence and therapy: Evolving translational strategies*. Critical Care Medicine 2009, 37 (5) , 1777-1786. https://doi.org/10.1097/CCM.0b013e31819ff137
97. Robert L. Giles, John D. Sullivan, Andrew M. Steiner, Ryan E. Looper. Addition–Hydroamination Reactions of Propargyl Cyanamides: Rapid Access to Highly Substituted 2‐Aminoimidazoles. Angewandte Chemie International Edition 2009, 48 (17) , 3116-3120. https://doi.org/10.1002/anie.200900160
98. Robert L. Giles, John D. Sullivan, Andrew M. Steiner, Ryan E. Looper. Addition–Hydroamination Reactions of Propargyl Cyanamides: Rapid Access to Highly Substituted 2‐Aminoimidazoles. Angewandte Chemie 2009, 121 (17) , 3162-3166. https://doi.org/10.1002/ange.200900160
99. Steven A. Rogers, Michael Krayer, Jonathan S. Lindsey, Christian Melander. Tandem dispersion and killing of bacteria from a biofilm. Org. Biomol. Chem. 2009, 7 (3) , 603-606. https://doi.org/10.1039/B817923A
100. Zhong Jin. Muscarine, imidazole, oxazole and thiazole alkaloids. Natural Product Reports 2009, 26 (3) , 382. https://doi.org/10.1039/b718045b